Mouse pups born from eggs derived from the granulosa cells that surround oocytes

(Cell Press) By introducing a chemical cocktail to granulosa cells, researchers in China induced the cells to transform into functional oocytes in mice. Once fertilized, these oocytes were then successfully able to produce healthy offspring, showing no differences from naturally bred mice. The chemical reprogramming method appears Dec. 24, 2019, in the journal Cell Reports.